Sildenafil is excreted as metabolites predominantly from the feces (about 80% of administered oral dose) also to a lesser extent inside the urine (close to thirteen% of the administered oral dose). If taken using a higher-Extra fat meal, absorption is minimized; enough time taken to achieve the most plasma concentration will increase by close to one hour, and the maximum focus itself is decreased by just about a person-3rd. Route of administration
Stay away from working with any other medicines to take care of impotence, for example alprostadil or yohimbine, without the need of initially conversing with your health practitioner.
Viagra can assist you have an erection when sexual stimulation takes place. An erection will likely not come about just by having a tablet. Abide by your medical doctor's Guidelines.
 The Viagra identify is now so famous, several bogus aphrodisiacs now simply call them selves "herbal viagra" or are introduced as blue tablets imitating The form and colour of Pfizer's product or service. Viagra is additionally informally often called "vitamin V", "the blue capsule", or "blue diamond", as well as various other nicknames.
Sildenafil citrate 100 mg commencing dose in Guys with erectile dysfunction in an international, double-blind, placebo-controlled study: effect on the sexual experience and reducing inner thoughts of stress and anxiety with regard to the future intercourse endeavor.
Whilst sildenafil enhances some markers of ailment in those with pulmonary arterial hypertension, it doesn't seem to have an effect on the chance of Dying or serious Negative effects as of 2014[update]. Raynaud's phenomenon
You should bring this checklist with you each time you pay a visit to a physician or For anyone sildenafil citrate who is admitted to your medical center. It is additionally important information and facts to hold with you in the event of emergencies.
Whilst the sale stays subject to a session that has a pharmacist, one other limitations in the demo are actually eliminated, letting buyers above the age of eighteen to get a vast number of tablets [fifty six] The decision was manufactured, partially, to reduce on the internet product sales of counterfeit and likely dangerous erectile dysfunction therapies.
-This drug is indicated for cure of erectile dysfunction in male Grownup individuals, and is likewise promoted as Revatio (R) to treat PAH in youngsters and adults.
If you're taking sildenafil to treat erectile dysfunction, tell your physician if you have ever been recommended by a healthcare Experienced in order to avoid sexual activity for professional medical explanations or if you have at any time expert upper body pain all through sexual action.
Sildenafil and various PDE5 inhibitors are utilised off-label to ease vasospasm and treat severe ischemia and ulcers in fingers and toes for people with secondary Raynaud's phenomenon;[nine][ten] these prescription drugs have reasonable efficacy for decreasing the frequency and period of vasospastic episodes.
Using sildenafil and an α1 blocker (ordinarily prescribed for hypertension or for urologic conditions, such as benign prostatic hypertrophy) simultaneously may bring about small blood pressure, but this result will not manifest If they're taken at the very least four several hours apart. Contraindications
Usually do not consider sildenafil When you are also using a nitrate drug for chest suffering or coronary heart complications, together with nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, plus some leisure medicine including "poppers". Having sildenafil with a nitrate medicine may cause a sudden and significant lower in hypertension.
All those working with protease inhibitors are proposed to Restrict their usage of sildenafil to no multiple twenty five mg dose every 48 hrs.[two] Other medicine that interfere Along with the metabolism of sildenafil contain erythromycin and cimetidine, both of which often can also bring on extended plasma 50 %-daily life concentrations.